4-Perhydroazepinone hydrochloride
Base Information
- Chemical Name: 4-Perhydroazepinone hydrochloride
- CAS No.: 50492-22-3
Cost-effective customized wholesale 4-Perhydroazepinone hydrochloride 50492-22-3
- Molecular Formula: C6H12ClNO
- Molecular Weight: 149.62
- Melting Point: 176-181℃
- Flash Point: 152°(306°F)
- PSA： 29.10000
- LogP: 1.45980
4-Perhydroazepinone hydrochloride(Cas 50492-22-3) Usage
InChI:InChI=1/C6H11NO.ClH/c8-6-2-1-4-7-5-3-6;/h7H,1-5H2;1H
50492-22-3 Relevant articles
CONJUGATED PROTEINS AND USES THEREOF
-
Paragraph 0387; 0411-0412, (2020/09/16)
Disclosed herein, in certain embodiments...
DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
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Page/Page column 19, (2018/04/20)
This invention relates to new inhibitors...
NOVEL COMPOUNDS
-
Paragraph 0487; 0488, (2013/06/26)
This invention relates to compounds of f...
NOVEL COMPOUNDS
-
Paragraph 0416; 0417, (2013/06/27)
This invention relates to compounds of f...
50492-22-3 Process route
-
-
623-73-4
diazoacetic acid ethyl ester
-
-
29976-53-2
N-ethoxycarbonyl-4-piperidone
-
-
50492-22-3
azepan-4-one hydrochloride
| Conditions | Yield |
|---|---|
|
diazoacetic acid ethyl ester; N-ethoxycarbonyl-4-piperidone;
With
boron trifluoride diethyl etherate;
In
diethyl ether;
at -35 ℃;
for 1.5h;
With
hydrogenchloride;
In
water;
for 6h;
Heating / reflux;
|
88%
|
|
diazoacetic acid ethyl ester; N-ethoxycarbonyl-4-piperidone;
With
boron trifluoride diethyl etherate;
In
diethyl ether;
at -35 ℃;
for 1.5h;
With
hydrogenchloride; water;
for 6h;
Heating / reflux;
|
88%
|
-
-
141642-82-2
5-oxo-azepane-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester
-
-
50492-22-3
azepan-4-one hydrochloride
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water;
for 15h;
Reflux;
|
100%
|
|
With
hydrogenchloride;
for 6h;
Heating;
|
84%
|
|
With
hydrogenchloride; water;
for 4h;
Heating / reflux;
|
|
|
With
hydrogenchloride;
In
water;
for 7h;
Heating / reflux;
|
|
|
With
hydrogenchloride;
In
water;
at 110 ℃;
|
11 g
|
|
With
hydrogenchloride;
In
water;
at 110 ℃;
|
11 g
|
|
With
hydrogenchloride;
In
water;
at 110 ℃;
|
11 g
|
|
With
hydrogenchloride;
In
water;
at 110 ℃;
for 6h;
|
50492-22-3 Upstream products
-
19786-58-4
5-oxoazepane-1,4-dicarboxylic acid diethyl ester
-
141642-82-2
5-oxo-azepane-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester
-
29976-53-2
N-ethoxycarbonyl-4-piperidone
-
623-73-4
diazoacetic acid ethyl ester
50492-22-3 Downstream products
-
56515-89-0
ethyl hexahydro-4-oxo-1H-azepine-1-carboxylate
-
143943-95-7
1-benzyl-4-(propananilido)perhydroazepine
-
74134-07-9
4-anilinoperhydroazepine
-
143944-00-7
4-(propananilido)perhydroazepine