Diclofenac potassium
Base Information
- Chemical Name: Diclofenac potassium
- CAS No.: 15307-81-0
Manufacturer supply top purity Diclofenac potassium 15307-81-0 with ISO standards We provide high quality Diclofenac potassium (CAS 15307-81-0), at a very affordable prices to our customers.
1.What is the Diclofenac potassium ?
Dichlofenac potassium is the potassium salt of dichlofenac. It is a nonsteroidal anti-inflammatory agent that can be used to reduce inflammation and as an analgesic to reduce pain in certain conditions. It can also used to treat dysmenorrhea. It can treat inflammatory disorders such as musculoskeletal complaints, dental pain, arthritis, actinic keratosis, joint pain, acute pain and chronic pain caused by certain kinds of cancers. Traditional opinion proposes that diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency. However, recent studies have shown that the pharmacologic activity of diclofenac goes beyond COX inhibition, and includes multimodal and, in some instances, novel mechanisms of action (MOA). For example, research suggests diclofenac can inhibit the thromboxane-prostanoid receptor, affect arachidonic acid release and uptake, inhibit lipoxygenase enzymes, and activate the nitric oxide–cGMP antinociceptive pathway. Other novel MOAs may include the inhibition of substrate P, inhibition of peroxisome proliferator activated receptor gamma (PPARγ), blockage of acid-sensing ion channels, alteration of interleukin-6 production, and inhibition of N-methyl-D-aspartate (NMDA) receptor hyperalgesia.
Cyclo-oxygenase inhibitor; analgesic; anti-inflammatory.
2.What is the CAS number for Diclofenac potassium ?
The CAS number of Diclofenac potassium is 15307-81-0.
More information of Diclofenac potassium 15307-81-0 are:
|
CAS?Number |
15307-81-0 |
|
Melting Point |
156-158oC |
|
Boiling Point |
412 °C at 760 mmHg |
|
Flash Point |
203 °C |
|
Vapor Pressure |
1.59E-07mmHg at 25°C |
|
HS CODE |
2922492050 |
|
PSA |
52.16000 |
|
LogP |
3.10240 |
3.What is the molecular formula of Diclofenac potassium ?
The chemical formula of?Diclofenac potassium is C14 H10 Cl2 NO2 *K which containing 14 Carbon atoms,10 Hydrogen atoms,2 Chlorine atoms,1 Nitrogen atoms,1 Oxygen atoms and 1 Potassium atoms,and the molecular weight, and the molecular weight of Diclofenac potassium is 334.243
4.What is Diclofenac potassium(15307-81-0)used for?
Dichlofenac potassium is the potassium salt of dichlofenac. It is a nonsteroidal anti-inflammatory agent that can be used to reduce inflammation and as an analgesic to reduce pain in certain conditions. It can also used to treat dysmenorrhea. It can treat inflammatory disorders such as musculoskeletal complaints, dental pain, arthritis, actinic keratosis, joint pain, acute pain and chronic pain caused by certain kinds of cancers. Traditional opinion proposes that diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency. However, recent studies have shown that the pharmacologic activity of diclofenac goes beyond COX inhibition, and includes multimodal and, in some instances, novel mechanisms of action (MOA). For example, research suggests diclofenac can inhibit the thromboxane-prostanoid receptor, affect arachidonic acid release and uptake, inhibit lipoxygenase enzymes, and activate the nitric oxide–cGMP antinociceptive pathway. Other novel MOAs may include the inhibition of substrate P, inhibition of peroxisome proliferator activated receptor gamma (PPARγ), blockage of acid-sensing ion channels, alteration of interleukin-6 production, and inhibition of N-methyl-D-aspartate (NMDA) receptor hyperalgesia.
InChI:InChI=1/C14H11Cl2NO2.K/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1
Relevant articles related to Diclofenac potassium:
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Article |
Source |
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PROCESS FOR THE PREPARATION OF DICLOFENAC EPOLAMINE |
- Page/Page column 8-9, (2010/08/05) |
5.Manufacturer supply top purity Diclofenac potassium 15307-81-0 with ISO standards
Shanghai chamflyer chemicals Co., Ltd is a quality supplier of Diclofenac potassium. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Diclofenac potassium 15307-81-0.