Menadione

Base Information

  • Chemical Name: Menadione
  • CAS No.: 58-27-5

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1.What is the Menadione ?

Vitamin K is a general term referring to a group of naphthoquinone derivatives required in the diet for blood clotting. Menadione is a fat-soluble vitamin that is essential for blood clotting. It is destroyed by irradiation during processing but has no appreciable loss during storage. It occurs in spinach, cabbage, liver, and wheat bran.

Vitamin K activity is associated with several quinones, including phylloquinone (vitamin K1), menadione (vitamin K3), and a variety of menaquinones (vitamin K2). These quinones promote the synthesis of proteins that are involved in the coagulation of blood.These proteins include prothrombin, factor VII (proconvertin), factor IX (plasma thromboplastin). The vitamin K quinones are obtained from three major sources.Vitamin K is present in various plants, especially green vegetables. The menaquinones that possess vitamin K2 activity are synthesized by bacteria, particularly gram-positive organisms; the bacteria in the gut of animals produce useful quantities of this vitamin.Vitamin K3 is a chemically synthesized quinone that possesses the same activity as vitamin K1.

Menadione is precursor to verious types of Vitamin K. It is of industrial importance as an intermediate in the synthesis of phylloquinone, and salts of its bisulfite adduct are used as stabilized forms in the animal feed industry. Commercially significant forms are menadione sodium bisulfite and menadione dimethyl pyrimidinol. Used as a micronutrient for livestock and pet foods.

2.What is the CAS number for Menadione ?

The CAS number of Menadione is 58-27-5.

More information of Menadione 58-27-5 are:

CAS?Number

58-27-5

Density

1.225 g/cm3

Melting Point

105-107 °C(lit.)

Boiling Point

304.5 °C at 760 mmHg

Flash Point

113.8 °C

Refractive Index

1.5500 (estimate)

HS CODE

29147000

PSA

34.14000

LogP

2.01190

3.What is the molecular formula of Menadione ?

The chemical formula of?Menadione is C11H8O2 which containing 11 Carbon atoms,8 Hydrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of Menadione is 172.183

4.What is Menadione(58-27-5)used for?

Vitamin K is a general term referring to a group of naphthoquinone derivatives required in the diet for blood clotting. Menadione is a fat-soluble vitamin that is essential for blood clotting. It is destroyed by irradiation during processing but has no appreciable loss during storage. It occurs in spinach, cabbage, liver, and wheat bran.

InChI:InChI=1/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3

Relevant articles related to Menadione:

Article

Source

A new metal-free access to vitamin K3

Bohle, Anne,Schubert, Anett,Sun, Yu,Thiel, Werner R.

, p. 1011 - 1015 (2006)

Manganese(II) naphthenate as effective catalyst for the clean oxidation of 2-methylnaphthalene by hydrogen peroxide

Yan, Tingfeng,Hong, Mei,Niu, Lei,Jiang, Feng,Xiao, Guomin

, p. 1839 - 1846 (2012)

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