Carbobenzoxyhydrazide
Base Information
- Chemical Name: Carbobenzoxyhydrazide
- CAS No.: 5331-43-1
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1.What is the Carbobenzoxyhydrazide ?
Benzyl carbazate is used as a reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method. It is also used in the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation.
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22129-07-3
N-benzyloxycarbonylimidazole
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5331-43-1
N-benzyloxycarbonyl-hydrazine
| Conditions | Yield |
|---|---|
|
With
hydrazine hydrate;
In
tetrahydrofuran;
at 20 ℃;
|
95%
|
|
With
hydrazine hydrate;
In
dichloromethane;
at 0 - 20 ℃;
for 1.5h;
|
5.78 g
|
-
-
3459-92-5
DBC
-
-
5331-43-1
N-benzyloxycarbonyl-hydrazine
| Conditions | Yield |
|---|---|
|
With
hydrazine hydrate;
at 110 ℃;
|
|
|
With
hydrazine hydrate;
auf dem Dampfbad;
|
|
|
With
hydrazine hydrate;
In
isopropyl alcohol;
|
2.What is the CAS number for Carbobenzoxyhydrazide ?
The CAS number of Carbobenzoxyhydrazide is 5331-43-1.
More information of Carbobenzoxyhydrazide 5331-43-1 are:
|
CAS?Number |
5331-43-1 |
|
Density |
1.202 g/cm3 |
|
Melting Point |
65-68 °C(lit.) |
|
Boiling Point |
351.292 °C at 760 mmHg |
|
Flash Point |
166.255 °C |
|
Refractive Index |
1.6180 (estimate) |
|
HS CODE |
29280000 |
|
PSA |
64.35000 |
|
LogP |
1.87770 |
|
Pka |
10.56±0.20(Predicted) |
3.What are another words for Carbobenzoxyhydrazide ?
Synonyms?for?Carbobenzoxyhydrazide 5331-43-1:Carbazicacid, benzyl ester (6CI,7CI,8CI);Benzylhydrazinecarboxylate;Benzyl hydrazinocarboxylate;Benzyloxycarbonyl hydrazide;Hydrazincarboxylic acid benzylester;NSC 2287;[(Benzyloxy)carbonyl]hydrazine;Carbazic acid, benzyl ester;
4.What is the molecular formula of Carbobenzoxyhydrazide?
The chemical formula of ?Carbobenzoxyhydrazide is?C8H10N2O2 which containing 8 Carbon atoms,10 Hydrogen atoms,2 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??Carbobenzoxyhydrazide?is 166.18.
5.What is Carbobenzoxyhydrazide (5331-43-1) used for?
Carbobenzoxyhydrazide, also known as Z-hydrazide or Carbobenzoxy-L-phenylalanine hydrazide, is a chemical compound derived from hydrazides. It is characterized by its reactivity and ability to form derivatives with other molecules, making it a versatile compound in various chemical and pharmaceutical applications.
InChI:InChI=1/C8H10N2O2/c9-10-8(11)12-6-7-4-2-1-3-5-7/h1-5H,6,9H2,(H,10,11)
Relevant articles related to Carbobenzoxyhydrazide:
|
Article |
Source |
|
Method for synthesizing benzyl hydrazinecarboxylate |
- Paragraph 0016; 0034-0065, (2019/05/04) |
|
Hydrazine carboxylic acid benzyl ester synthesis method |
- Paragraph 0024-0027, (2017/04/25) |
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